Research in the Works

Tisugen Therapeutics Osteoarthritis (OA) Knee Pain and Repair Study
Damage to knee cartilage from the wear-and-tear of aging and/or athletic trauma can cause severe pain, cartilage degeneration, and immobility. Tisugen Therapeutics, LLC, has been approved by the Western Institutional Review Board (WIRB) to proceed with human subject research that will study a new minimally invasive treatment believed to provide pain relief and potential repair and regeneration of knee cartilage during an intermittent 28-day treatment of osteoarthritis of the knee.

Treatment is provided through an electrotherapy stimulation biomedical device that is sub-sensory (barely, if at all, noticeable) and is minimally invasive. Electrotherapy is a treatment that has long been used to treat pain for various ailments by licensed acupuncturists and, in recent years, many medical doctors are also employing it as analgesia for chronic pain.

Approximately 60 men and women, ages 40 to 75, will be selected for the study. Subjects will need to have received a diagnosis of Grade II or III osteoarthritis for one or both knees and be willing to come to the UNC Community Clinic for one hour, twice weekly treatments during the four-week trial.

For more information, call the University of Northern California Community Clinic at (707) 664-6365.